Transannular nitrone cycloaddition. A stereocontrolled entry to the spirocyclic core of pinnaic acid.
نویسندگان
چکیده
[figure: see text] Thermolysis of lactone 18 initiated a stereospecific transannular nitrone-olefin [3 + 2] cycloaddition to yield tetracycle 19. Methanolysis followed by reductive cleavage of the isoxazolidine yielded 20, representing the azaspirocyclic core of pinnaic acid (1).
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 3 3 شماره
صفحات -
تاریخ انتشار 2001